Development and Evaluation of Oral Herbal Formulations of Lantana Camara Extract

نویسندگان

  • BIRESH KUMAR SARKAR
  • RAMAIAH MADDI
  • MANISH DEVGAN
چکیده

1 National Institute of Ayurvedic Pharmaceutical Research, Moti Bagh Road, Patiala, Punjab, India. 2 Department of Pharmacognosy, Hindu College of Pharmacy, Guntur, A.P. 522002, India. 3 Faculty of Pharmacy, R.P. Educational Trust Group of Institutions, Karnal, Haryana, India. 4 NRI College of pharmacy, Krishna Dt., A.P., India. * Corresponding Author’ Email: [email protected] --------------------------------------------------------------------------------------------------------------------------------------------ABSTRACT: In the present investigation, orally administrable dosage forms of Lantana camara extract were developed. Two formulations from liquid class were designed and developed. By considering difficulty of solubility of herbal drugs in a vehicle, in one of the liquid class, decoction form of drugs in specific vehicle was used. This form of drugs hereafter considered as Liquid Oral Dosage Form of drugs. To prepare a liquid form with suspended particles of drugs, Suspension form was also designed. Formulated dosage forms then subjected to evaluation by different methods stated as per official compendia. Evaluation parameters observed optimum range of formulations which suggest suitability of such oral herbal dosage forms for the formulation of Lantana camara extract.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lantana Camara Linn. Chemical Constituents and Medicinal Properties: A Review

India has a rich tradition of plant based knowledge in health care. Among the large number of herbal drugs existing in India, very few have been studied systematically so far. Lantana camara is an evergreen plant found throughout India. Traditionally it has been used in treating various ailments and they were supported by scientific data’s. Various literatures have reported the phytoconstituent...

متن کامل

Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract.

BACKGROUND The objective of this study was to investigate the toxicity of Lantana camara methanol extract. METHODS In order to evaluate the toxicity of Lantana camara, the acute toxicity of the methanolic extract on adult mice and cytotoxicity test on Vero cell line were investigated. A fixed large dose of 2 g/kg body weight of L. camara leaf extract was administrated by a single oral gavage ...

متن کامل

Evaluatio ( of Some Medici ( Al Pla ( Ts for Their Da ( Druff Co ( Trol Properties

Dandruff caused by Malassezia spp is controlled by antifungal agents. In the present study four medicinal plantsTerminalia bellerica, Terminalia chebula, Emblica officinalis and Lantana camarawere selected to check their antifungal activity. Their efficacy was tested using different concentrations of extracts in various solvents. The antifungal activity of the plant extracts was determined by w...

متن کامل

In vivo toxicity study of Lantana camara.

OBJECTIVE To investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina. METHODS The methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay. RESULTS All the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most...

متن کامل

Evaluation of antimotility effect of Lantana camara L. var. acuelata constituents on neostigmine induced gastrointestinal transit in mice

BACKGROUND Lantana camara L. (Verbenaceae), a widely growing shrub which is toxic to some animal species, has been used in the traditional medicine for treating many ailments. The purpose of the present study was to evaluate the antimotility effects of Lantana camara leaf constituents in mice intestine. METHODS Evaluation of antimotility activity was done in intestine of mice treated with Lan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013